PMID:4879569

Citation	Helling, RB (1968) Selection of a mutant of Escherichia coli which has high mutation rates.J. Bacteriol. 96:975-80
Abstract	A mutation which causes high mutation rates in all other loci tested was induced with nitrosoguanidine and was selected through the ability of the progeny of such mutant cells to mutate to streptomycin resistance at a higher rate than the wild-type cells. This mutation (mut-2) and the Treffers' mutation (mutT1) mapped at approximately the same position to the right of leu. Specificity studies showed that the two mutations differ in rates of mutation produced.
Links	PubMed
Keywords	Crosses, Genetic; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Lysogeny; Mutagens; Mutation; Nitroso Compounds; Selection, Genetic; Streptomycin; Transduction, Genetic
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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: NCBI Taxon ID: 8333	Genotype of Reference Strain: mutT Genotype of Experimental Strain : mutT1	Reference Condition:					Streptomycin resistance (table 1). Other strains with same phenotype are described.
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