Difference between revisions of "PMID:19054113"

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{|  id="Q50574cd83b4f7"  class=" tableEdit PMID_info_table" 
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!align=left  |Citation
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'''Bochner, BR '''  (2009) Global phenotypic characterization of bacteria. ''FEMS Microbiol. Rev.'' '''33''':191-205
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!align=left  |Abstract
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The measure of the quality of a systems biology model is how well it can reproduce and predict the behaviors of a biological system such as a microbial cell. In recent years, these models have been built up in layers, and each layer has been growing in sophistication and accuracy in parallel with a global data set to challenge and validate the models in predicting the content or activities of genes (genomics), proteins (proteomics), metabolites (metabolomics), and ultimately cell phenotypes (phenomics). This review focuses on the latter, the phenotypes of microbial cells. The development of Phenotype MicroArrays, which attempt to give a global view of cellular phenotypes, is described. In addition to their use in fleshing out and validating systems biology models, there are many other uses of this global phenotyping technology in basic and applied microbiology research, which are also described.
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19054113 PubMed] [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704929 PMC2704929]
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Online version:[http://dx.doi.org/10.1111/j.1574-6976.2008.00149.x 10.1111/j.1574-6976.2008.00149.x]
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!align=left  |Keywords
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Bacteria/classification; Bacteria/genetics; Bacteria/metabolism; Bacteria/pathogenicity; Industrial Microbiology; Metabolic Networks and Pathways; Oligonucleotide Array Sequence Analysis; Phenotype; Signal Transduction; Systems Biology
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==Main Points of the Paper ==
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{{LitSignificance}}
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== Materials and Methods Used ==
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{{LitMaterials}}
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==Phenotype Annotations==
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{|  id="V50574cd8493ba"  class=" tableEdit Phenotype_Table_2" 
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!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
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==Notes==
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==References==
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{{RefHelp}}
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<references/>
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[[Category:Publication]]
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[[Category:Phenotype Microarray (PM), Biolog]]

Latest revision as of 11:16, 17 September 2012

Citation

Bochner, BR (2009) Global phenotypic characterization of bacteria. FEMS Microbiol. Rev. 33:191-205

Abstract

The measure of the quality of a systems biology model is how well it can reproduce and predict the behaviors of a biological system such as a microbial cell. In recent years, these models have been built up in layers, and each layer has been growing in sophistication and accuracy in parallel with a global data set to challenge and validate the models in predicting the content or activities of genes (genomics), proteins (proteomics), metabolites (metabolomics), and ultimately cell phenotypes (phenomics). This review focuses on the latter, the phenotypes of microbial cells. The development of Phenotype MicroArrays, which attempt to give a global view of cellular phenotypes, is described. In addition to their use in fleshing out and validating systems biology models, there are many other uses of this global phenotyping technology in basic and applied microbiology research, which are also described.

Links

PubMed PMC2704929 Online version:10.1111/j.1574-6976.2008.00149.x

Keywords

Bacteria/classification; Bacteria/genetics; Bacteria/metabolism; Bacteria/pathogenicity; Industrial Microbiology; Metabolic Networks and Pathways; Oligonucleotide Array Sequence Analysis; Phenotype; Signal Transduction; Systems Biology

Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

</protect>

Notes

References

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