PMID:19054113

Citation	Bochner, BR (2009) Global phenotypic characterization of bacteria. FEMS Microbiol. Rev. 33:191-205
Abstract	The measure of the quality of a systems biology model is how well it can reproduce and predict the behaviors of a biological system such as a microbial cell. In recent years, these models have been built up in layers, and each layer has been growing in sophistication and accuracy in parallel with a global data set to challenge and validate the models in predicting the content or activities of genes (genomics), proteins (proteomics), metabolites (metabolomics), and ultimately cell phenotypes (phenomics). This review focuses on the latter, the phenotypes of microbial cells. The development of Phenotype MicroArrays, which attempt to give a global view of cellular phenotypes, is described. In addition to their use in fleshing out and validating systems biology models, there are many other uses of this global phenotyping technology in basic and applied microbiology research, which are also described.
Links	PubMed PMC2704929 Online version:10.1111/j.1574-6976.2008.00149.x
Keywords	Bacteria/classification; Bacteria/genetics; Bacteria/metabolism; Bacteria/pathogenicity; Industrial Microbiology; Metabolic Networks and Pathways; Oligonucleotide Array Sequence Analysis; Phenotype; Signal Transduction; Systems Biology
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Materials and Methods Used

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Phenotype Annotations

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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
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