Difference between revisions of "PMID:6760806"

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!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
 
!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain: B1466
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''ompF''
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*Genotype of Experimental Strain : ''ompF1466''
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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Resistance to beta lactam ampicillin
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain: B1466
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''ompF''
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*Genotype of Experimental Strain : ''ompF1466''
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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Resistance to beta lactam Cefoxitin
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain: B1436
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''ompB''
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*Genotype of Experimental Strain : ''ompB1422''
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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 +
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 +
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Resistance to beta lactam Cefoxitin
 +
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 +
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|-
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a mutation or genetic difference within a strain
 +
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*Taxon: Escherichia coli
 +
*Strain: K-12
 +
*Substrain: B1436
 +
*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''ompB''
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*Genotype of Experimental Strain : ''ompB1422''
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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|
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|
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Resistance to beta lactam ampicillin
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==Notes==
 
==Notes==
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ECO: The term Solid medium (in vivo) is awaiting approval to add.
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OMP:
  
 
==References==
 
==References==

Latest revision as of 18:00, 23 January 2013

Citation

Jaffe, A, Chabbert, YA and Semonin, O (1982) Role of porin proteins OmpF and OmpC in the permeation of beta-lactams.Antimicrob. Agents Chemother. 22:942-8

Abstract

Mutants of Escherichia coli K-12 lacking major outer membrane proteins were obtained by selecting for resistance to the beta-lactam cefoxitin. Three classes of resistant strains were found: mutants in ompB, a regulatory locus for proteins OmpF and OmpC; mutants in ompF; and one mutant in tpo. The OmpF and OmpC proteins facilitate penetration of beta-lactams through the outer membrane.

Links

PubMed

Keywords

Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Cell Membrane Permeability; Escherichia coli; Hexosyltransferases; Membrane Proteins; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; beta-Lactams

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Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: B1466
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: ompF
  • Genotype of Experimental Strain : ompF1466
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

Resistance to beta lactam ampicillin

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: B1466
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: ompF
  • Genotype of Experimental Strain : ompF1466
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

Resistance to beta lactam Cefoxitin

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: B1436
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: ompB
  • Genotype of Experimental Strain : ompB1422
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

Resistance to beta lactam Cefoxitin

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: B1436
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: ompB
  • Genotype of Experimental Strain : ompB1422
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

Resistance to beta lactam ampicillin


edit table

</protect>

Notes

ECO: The term Solid medium (in vivo) is awaiting approval to add.

OMP:

References

See Help:References for how to manage references in omp dev.

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