Difference between revisions of "PMID:4879569"

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{|  id="K4f95a1fd716e9"  class=" tableEdit PMID_info_table" 
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!align=left  |Citation
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'''Helling, RB'''  (1968) Selection of a mutant of Escherichia coli which has high mutation rates.''J. Bacteriol.'' '''96''':975-80
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!align=left  |Abstract
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A mutation which causes high mutation rates in all other loci tested was induced with nitrosoguanidine and was selected through the ability of the progeny of such mutant cells to mutate to streptomycin resistance at a higher rate than the wild-type cells. This mutation (mut-2) and the Treffers' mutation (mutT1) mapped at approximately the same position to the right of leu. Specificity studies showed that the two mutations differ in rates of mutation produced.
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!align=left  |Links
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=4879569 PubMed]
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!align=left  |Keywords
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Crosses, Genetic; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Lysogeny; Mutagens; Mutation; Nitroso Compounds; Selection, Genetic; Streptomycin; Transduction, Genetic
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==Main Points of the Paper ==
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{{LitSignificance}}
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== Materials and Methods Used ==
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{{LitMaterials}}
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==Phenotype Annotations==
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="W4f95a1fd8099a"  class=" tableEdit Phenotype_Table_2" 
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!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain:
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 8333]
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*Genotype of Reference Strain: ''mutT''
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*Genotype of Experimental Strain : ''mutT1''
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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ECO:0000182
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in vitro culture assay data
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Streptomycin resistance (table 1). Other strains with same phenotype are described.
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==Notes==
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==References==
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{{RefHelp}}
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<references/>
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[[Category:Publication]] [[Category:Papers referenced in the LaRossa chapter]]

Latest revision as of 12:34, 25 January 2013

Citation

Helling, RB (1968) Selection of a mutant of Escherichia coli which has high mutation rates.J. Bacteriol. 96:975-80

Abstract

A mutation which causes high mutation rates in all other loci tested was induced with nitrosoguanidine and was selected through the ability of the progeny of such mutant cells to mutate to streptomycin resistance at a higher rate than the wild-type cells. This mutation (mut-2) and the Treffers' mutation (mutT1) mapped at approximately the same position to the right of leu. Specificity studies showed that the two mutations differ in rates of mutation produced.

Links

PubMed

Keywords

Crosses, Genetic; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Lysogeny; Mutagens; Mutation; Nitroso Compounds; Selection, Genetic; Streptomycin; Transduction, Genetic

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Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 8333
  • Genotype of Reference Strain: mutT
  • Genotype of Experimental Strain : mutT1
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

ECO:0000182

in vitro culture assay data

Streptomycin resistance (table 1). Other strains with same phenotype are described.


edit table

</protect>

Notes

References

See Help:References for how to manage references in omp dev.

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