PMID:4939769

Citation	Dempsey, WB and Arcement, LJ (1971) Identification of the forms of vitamin B 6 present in the culture media of "vitamin B 6 control" mutants.J. Bacteriol. 107:580-2
Abstract	An Escherichia coli mutant resistant to isoniazid (WG497) contained 0.6 mumole of extracellular pyridoxamine and pyridoxamine phosphate in the early stationary phase. A suppressed lysine mutant (AT1024) contained 1.4 mumoles of pyridoxal phosphate under the same conditions. The internal concentration of vitamin B(6) was one-half of normal for AT1024 and increased fivefold for WG497.
Links	PubMed
Keywords	Biological Assay; Cell Membrane Permeability; Cell-Free System; Culture Media; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Isoniazid; Mutation; Picolines; Pyridoxal Phosphate; Pyridoxine; Toluene; Yeasts
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Phenotype Annotations

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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: WG497 NCBI Taxon ID: 83333	Genotype of Reference Strain: pdx Genotype of Experimental Strain : pdx	Reference Condition:	OMP:0000276	increased resistance to antimicrobial compound	ECO:0000182	in vitro culture assay data	Resistant to Isoniazid
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