Difference between revisions of "PMID:6264273"

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{|  id="L5037f15058106"  class=" tableEdit PMID_info_table" 
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!align=left  |Citation
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'''Ostrowski, J and Hulanicka, D'''  (1981) Effect of DNA gyrase inhibitors on gene expression of the cysteine regulon.''Mol. Gen. Genet.'' '''181''':363-6
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!align=left  |Abstract
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Nalidixic acid inhibits the expression of those cysteine genes which are regulated by the cysB product, it has no affect, however, on the constitutively-expressed cysE gene. The expression of cysteine genes in a strain carrying a mutation in the nalA locus is resistant to this drug. Novobiocin affects the expression of cysteine genes similarly to nalidixic acid. The effect of nalidixic acid on the expression of genes in a cysteine constitutive mutant was studied.
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6264273 PubMed]
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!align=left  |Keywords
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Acetyltransferases; Cysteine; Cysteine Synthase; Gene Expression Regulation; Genes, Regulator; Mutation; Nalidixic Acid; Novobiocin; Oxidoreductases Acting on Sulfur Group Donors; Salmonella typhimurium; Serine O-Acetyltransferase; Topoisomerase II Inhibitors
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==Main Points of the Paper ==
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{{LitSignificance}}
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== Materials and Methods Used ==
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{{LitMaterials}}
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==Phenotype Annotations==
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="M5037f15072af3"  class=" tableEdit Phenotype_Table_2" 
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!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain:
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''cysB''
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*Genotype of Experimental Strain : ''cys2332''
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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Resistant to antibiotic nalidixic acid.
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==Notes==
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==References==
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{{RefHelp}}
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<references/>
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[[Category:Publication]]  [[Category:Papers referenced in the LaRossa chapter]] [[Category:LaRossa citations that need review]]

Latest revision as of 18:18, 23 January 2013

Citation

Ostrowski, J and Hulanicka, D (1981) Effect of DNA gyrase inhibitors on gene expression of the cysteine regulon.Mol. Gen. Genet. 181:363-6

Abstract

Nalidixic acid inhibits the expression of those cysteine genes which are regulated by the cysB product, it has no affect, however, on the constitutively-expressed cysE gene. The expression of cysteine genes in a strain carrying a mutation in the nalA locus is resistant to this drug. Novobiocin affects the expression of cysteine genes similarly to nalidixic acid. The effect of nalidixic acid on the expression of genes in a cysteine constitutive mutant was studied.

Links

PubMed

Keywords

Acetyltransferases; Cysteine; Cysteine Synthase; Gene Expression Regulation; Genes, Regulator; Mutation; Nalidixic Acid; Novobiocin; Oxidoreductases Acting on Sulfur Group Donors; Salmonella typhimurium; Serine O-Acetyltransferase; Topoisomerase II Inhibitors

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Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: cysB
  • Genotype of Experimental Strain : cys2332
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

Resistant to antibiotic nalidixic acid.


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</protect>

Notes

References

See Help:References for how to manage references in omp dev.

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