Difference between revisions of "PMID:2168148"

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'''Yoshida, H, Bogaki, M, Nakamura, M and Nakamura, S'''  (1990) Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.''Antimicrob. Agents Chemother.'' '''34''':1271-2
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!align=left  |Abstract
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Nucleotide sequence analysis of the gyrA genes of 10 spontaneous quinolone-resistant gyrA mutants of Escherichia coli KL16, including four mutants examined previously, disclosed that quinolone resistance was caused by a point mutation within the region between amino acids 67 and 106, especially in the vicinity of amino acid 83, of the GyrA protein.
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2168148 PubMed]
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4-Quinolones; Anti-Infective Agents; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Escherichia coli; Mutation
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==Main Points of the Paper ==
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{{LitSignificance}}
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== Materials and Methods Used ==
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==Phenotype Annotations==
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==Notes==
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==References==
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[[Category:Publication]]

Revision as of 11:23, 9 September 2012

Citation

Yoshida, H, Bogaki, M, Nakamura, M and Nakamura, S (1990) Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.Antimicrob. Agents Chemother. 34:1271-2

Abstract

Nucleotide sequence analysis of the gyrA genes of 10 spontaneous quinolone-resistant gyrA mutants of Escherichia coli KL16, including four mutants examined previously, disclosed that quinolone resistance was caused by a point mutation within the region between amino acids 67 and 106, especially in the vicinity of amino acid 83, of the GyrA protein.

Links

PubMed

Keywords

4-Quinolones; Anti-Infective Agents; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Escherichia coli; Mutation

Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

</protect>

Notes

References

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