PMID:2553680

Citation	Braun, V (1989) The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity. J. Bacteriol. 171:6387-90
Abstract	Double exbB tolQ mutants of Escherichia coli were completely resistant to bacteriophages T1 and phi 80, in contrast to strains with exbB or tolQ mutations, which were sensitive. Cells carrying mutations in exbB were partially tolerant to colicins B, D, and M and became fully tolerant by the introduction of tolQ mutations. This suggested involvement of both exbB and tolQ in tonB-dependent uptake.
Links	PubMed PMC210519
Keywords	Anti-Bacterial Agents/pharmacology; Bacterial Proteins/genetics; Colicins/pharmacology; Coliphages/genetics; Escherichia coli/drug effects; Escherichia coli/genetics; Escherichia coli/physiology; Escherichia coli Proteins; Ferrichrome/pharmacology; Genes, Bacterial; Mutation; T-Phages/genetics
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Phenotype Annotations

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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: GM1 NCBI Taxon ID: 83333	Genotype of Reference Strain: exbB+-tolQ+ Genotype of Experimental Strain : exbB--tolQ-	Reference Condition:	0000276	increased resistance to anitbiotics	0000181	in vitro assay evidence	Mutations to the exbB and tolQ genes caused resistance to T1 Phage.
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