Difference between revisions of "PMID:14430363"
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**inducible i<sup>+</sup> allele appears dominant over the constitutive i<sup>-</sup> allele | **inducible i<sup>+</sup> allele appears dominant over the constitutive i<sup>-</sup> allele | ||
| − | *The | + | *The idea that i<sup>+</sup> could control the synthesis of a destructive enzyme which removes an endogenous intracellular inducer was eliminated due to observation from this paper (Figure 1, curves C & D). |
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| + | *The presence of 5-methyltryptophan enhances mating efficiency | ||
| + | |||
| + | *The data in this paper may suggest that: | ||
| + | **an inducer-destroying enzyme is not responsible for the difference between inducibility and constitutivity | ||
| + | **the repressor is not a protein, although the authors state this conclusion is open to doubt (evidence to refute this conclusion is shown [[PMID:5330222|here]]). | ||
== Materials and Methods Used == | == Materials and Methods Used == | ||
Revision as of 17:24, 22 November 2010
| Citation |
PARDEE, AB and PRESTIDGE, LS (1959) On the nature of the repressor of beta-galactosidase synthesis in Escherichia coli.Biochim. Biophys. Acta 36:545-7 |
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| Abstract |
No abstract in PubMed |
| Links | |
| Keywords |
Escherichia coli; Glycoside Hydrolases |
| edit table |
Main Points of the Paper
- Hfr(z+i+) X F-(z-i-):
- within a few minutes of the time of entry of the z+i+ genes (which are closely linked) the synthesis of β-galactosidase commenced at maximal velocity in the absence of extracellular inducer
- inducible i+ allele appears dominant over the constitutive i- allele
- The idea that i+ could control the synthesis of a destructive enzyme which removes an endogenous intracellular inducer was eliminated due to observation from this paper (Figure 1, curves C & D).
- The presence of 5-methyltryptophan enhances mating efficiency
- The data in this paper may suggest that:
- an inducer-destroying enzyme is not responsible for the difference between inducibility and constitutivity
- the repressor is not a protein, although the authors state this conclusion is open to doubt (evidence to refute this conclusion is shown here).
Materials and Methods Used
Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).
Phenotype Annotations
<protect>
| Species | Taxon ID | Strain | Gene (if known) | OMP | Phenotype | Details | Evidence | Notes |
|---|---|---|---|---|---|---|---|---|
| edit table |
</protect>
