Difference between revisions of "PMID:23697806"
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| + | !align=left align='left' bgcolor='#CCCCFF' |Citation | ||
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| + | '''Hayles, J, Wood, V, Jeffery, L, Hoe, KL, Kim, DU, Park, HO, Salas-Pino, S, Heichinger, C and Nurse, P''' (2013) A genome-wide resource of cell cycle and cell shape genes of fission yeast. ''Open Biol'' '''3''':130053 | ||
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| + | !align=left align='left' bgcolor='#CCCCFF' |Abstract | ||
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| + | To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843 fission yeast deletion mutants (95.7% of total protein encoding genes) for their effects on these processes. A total of 513 genes have been identified as being required for cell cycle progression, 276 of which have not been previously described as cell cycle genes. Deletions of a further 333 genes lead to specific alterations in cell shape and another 524 genes result in generally misshapen cells. Here, we provide the first eukaryotic resource of gene deletions, which describes a near genome-wide set of genes required for the cell cycle and cell shape. | ||
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| + | !align=left align='left' bgcolor='#CCCCFF' |Links | ||
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| + | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=23697806 PubMed] [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866870 PMC3866870] | ||
| + | Online version:[http://dx.doi.org/10.1098/rsob.130053 10.1098/rsob.130053] | ||
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| + | !align=left align='left' bgcolor='#CCCCFF' |Keywords | ||
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| + | Cell Cycle/genetics; Computational Biology; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, cdc; Genome, Fungal; Humans; Mutagenesis; Phenotype; Schizosaccharomyces/cytology; Schizosaccharomyces/genetics; Schizosaccharomyces pombe Proteins/genetics | ||
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| + | ==Main Points of the Paper == | ||
| + | {{LitSignificance}} | ||
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| + | == Materials and Methods Used == | ||
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| + | ==Phenotype Annotations== | ||
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| + | !|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status | ||
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| + | ==Notes== | ||
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| + | ==References== | ||
| + | {{RefHelp}} | ||
| + | <references/> | ||
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| + | [[Category:Publication]] | ||
Latest revision as of 14:42, 11 September 2017
| Citation |
Hayles, J, Wood, V, Jeffery, L, Hoe, KL, Kim, DU, Park, HO, Salas-Pino, S, Heichinger, C and Nurse, P (2013) A genome-wide resource of cell cycle and cell shape genes of fission yeast. Open Biol 3:130053 |
|---|---|
| Abstract |
To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843 fission yeast deletion mutants (95.7% of total protein encoding genes) for their effects on these processes. A total of 513 genes have been identified as being required for cell cycle progression, 276 of which have not been previously described as cell cycle genes. Deletions of a further 333 genes lead to specific alterations in cell shape and another 524 genes result in generally misshapen cells. Here, we provide the first eukaryotic resource of gene deletions, which describes a near genome-wide set of genes required for the cell cycle and cell shape. |
| Links |
PubMed PMC3866870 Online version:10.1098/rsob.130053 |
| Keywords |
Cell Cycle/genetics; Computational Biology; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, cdc; Genome, Fungal; Humans; Mutagenesis; Phenotype; Schizosaccharomyces/cytology; Schizosaccharomyces/genetics; Schizosaccharomyces pombe Proteins/genetics |
Main Points of the Paper
Please summarize the main points of the paper.
Materials and Methods Used
Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).
Phenotype Annotations
See Help:AnnotationTable for details on how to edit this table.
<protect>
| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|
</protect>
Notes
References
See Help:References for how to manage references in omp dev.
