Difference between revisions of "PMID:8706607"

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'''Kassa, E , Tsega, E  and Gebre, W '''  (1996) Comparison of diagnostic methods for detection of Helicobacter pylori. ''East Afr Med J'' '''73''':239-41
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!align=left  |Abstract
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Of two hundred Ethiopian patients with dyspepsia, multiple biopsies were taken from the antrum of the stomach. Helicobacter pylori was cultured from 85% of duodenal ulcer and in 75% of chronic antral gastritis patients. The overall Helicobacter pylori positivity was 70%. The sensitivity, specificity, positive and negative predictive values of the tests as compared to culture were as follows, respectively: direct urease test 100%/87%/95%/100%, direct gram stain 60%/98%/99%/51%, histological gram stain 66%/97%/98%/56%, Giemsa stain 100%/97%/99%/100% and Gimenez stain 100%/87%/95%/100%. It is concluded that gram staining of direct tissue smear or histology is an insensitive method in the diagnosis of Helicobacter pylori. All the other tests, are shown to be valid. Urease test is an excellent test for provision of presumptive diagnosis of Helicobacter pylori while awaiting confirmation either by culture of histology.
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8706607 PubMed]
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Adolescent; Adult; Azure Stains/diagnostic use; Biopsy/methods; Breath Tests/methods; Female; Gastritis/diagnosis; Gastritis/enzymology; Gastritis/microbiology; Gentian Violet/diagnostic use; Helicobacter Infections/diagnosis; Helicobacter Infections/enzymology; Helicobacter pylori; Humans; Male; Middle Aged; Phenazines/diagnostic use; Predictive Value of Tests; Reproducibility of Results; Urease/analysis
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==Main Points of the Paper ==
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== Materials and Methods Used ==
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==Phenotype Annotations==
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==Notes==
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==References==
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[[Category:Publication]]

Latest revision as of 18:06, 15 September 2012

Citation

Kassa, E , Tsega, E and Gebre, W (1996) Comparison of diagnostic methods for detection of Helicobacter pylori. East Afr Med J 73:239-41

Abstract

Of two hundred Ethiopian patients with dyspepsia, multiple biopsies were taken from the antrum of the stomach. Helicobacter pylori was cultured from 85% of duodenal ulcer and in 75% of chronic antral gastritis patients. The overall Helicobacter pylori positivity was 70%. The sensitivity, specificity, positive and negative predictive values of the tests as compared to culture were as follows, respectively: direct urease test 100%/87%/95%/100%, direct gram stain 60%/98%/99%/51%, histological gram stain 66%/97%/98%/56%, Giemsa stain 100%/97%/99%/100% and Gimenez stain 100%/87%/95%/100%. It is concluded that gram staining of direct tissue smear or histology is an insensitive method in the diagnosis of Helicobacter pylori. All the other tests, are shown to be valid. Urease test is an excellent test for provision of presumptive diagnosis of Helicobacter pylori while awaiting confirmation either by culture of histology.

Links

PubMed

Keywords

Adolescent; Adult; Azure Stains/diagnostic use; Biopsy/methods; Breath Tests/methods; Female; Gastritis/diagnosis; Gastritis/enzymology; Gastritis/microbiology; Gentian Violet/diagnostic use; Helicobacter Infections/diagnosis; Helicobacter Infections/enzymology; Helicobacter pylori; Humans; Male; Middle Aged; Phenazines/diagnostic use; Predictive Value of Tests; Reproducibility of Results; Urease/analysis

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Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

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<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status
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Notes

References

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