PMID:4887878

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Citation

Arditti, RR, Scaife, JG and Beckwith, JR (1968) The nature of mutants in the lac promoter region. J. Mol. Biol. 38:421-6

Abstract

No abstract in PubMed

Links

PubMed

Keywords

Escherichia coli/radiation effects; Galactosidases/biosynthesis; Genes, Regulator; Lactose; Membrane Transport Proteins/biosynthesis; Mutation; Operon; Radiation Genetics; Transduction, Genetic; Ultraviolet Rays

Main Points of the Paper

Please summarize the main points of the paper.

  • Characterization of 4 isolated putative promoter mutants that severely reduce the maximum rate of expression of the lac operon
    • L1-small deletion which removes part of the promoter and an adjacent segment of the i gene
    • L8- transitional point mutation
    • L37-transitional point mutation
    • L29-transitional point mutation
  • L8 and L37 are repeats of the same mutation.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

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Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain:
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: Strain L8 & L37
  • Reference Condition:

Abolished utilization of Malibose.


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Notes

References

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