PMID:355890
| Citation |
Calos, MP (1978) DNA sequence for a low-level promoter of the lac repressor gene and an 'up' promoter mutation.Nature 274:762-5 |
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| Abstract |
The promoter for a weakly expressed constitutive gene, the lactose repressor gene (lacI), has been sequenced, along with an 'up' promoter mutation Iq. The 10-fold enhancement in I expression found in Iq is the result of a single base change at position -35. To facilitate the sequencing, the lacI gene was cloned in a small plasmid. |
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| Keywords |
Base Sequence; Binding Sites; DNA-Directed RNA Polymerases; Escherichia coli; Genes, Regulator; Lactose; Operon |
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Materials and Methods Used
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| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|
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