PMID:21453489
| Citation |
Poteete, AR (2011) Recombination phenotypes of Escherichia coli greA mutants.BMC Mol. Biol. 12:12 |
|---|---|
| Abstract |
The elongation factor GreA binds to RNA polymerase and modulates transcriptional pausing. Some recent research suggests that the primary role of GreA may not be to regulate gene expression, but rather, to promote the progression of replication forks which collide with RNA polymerase, and which might otherwise collapse. Replication fork collapse is known to generate dsDNA breaks, which can be recombinogenic. It follows that GreA malfunction could have consequences affecting homologous recombination. |
| Links |
PubMed Online version:10.1186/1471-2199-12-12 |
| Keywords |
Escherichia coli; Escherichia coli Proteins; Mutation; Phenotype; Rec A Recombinases; Recombination, Genetic; Transcription Factors |
| edit table |
Main Points of the Paper
Please summarize the main points of the paper.
Materials and Methods Used
Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).
Phenotype Annotations
See Help:AnnotationTable for details on how to edit this table.
<protect>
| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|
| edit table |
</protect>
Notes
References
See Help:References for how to manage references in omp dev.
