PMID:5327656

Citation	Bourgeois, S, Cohn, M and Orgel, LE (1965) Suppression of and complementation among mutants of the regulatory gene of the lactose operon of Escherichia coli.J. Mol. Biol. 14:300-2
Abstract	No abstract in PubMed
Links	PubMed
Keywords	Escherichia coli; Genes; Genetic Code; Lactose; Molecular Biology; Mutation
edit table

Main Points of the Paper

• The regulatory gene, i, codes for a protein whereas the operator gene, o, probably does not

Materials and Methods Used

• Parent Strain: Δlac su^-/ Fi^So⁺z⁺y⁺
  • i^S- dominant over i⁺ and not inducible by lactose sz 43
• 5 strains with suppressor mutations
  • su^-
  • su⁺¹
  • su⁺²
  • su⁺³
  • su⁺⁴

Phenotype Annotations

<protect>

Species	Taxon ID	Strain	Gene (if known)	OMP	Phenotype	Details	Evidence	Notes
Escherichia coli	NCBI:562	Δlac su- /Fiso+z+y+		deficient in lactose metabolism (lac-)	Metabolic Activity		Biochemical Assay	LacZ assay
edit table

</protect>