PMID:23697806

Citation	Hayles, J, Wood, V, Jeffery, L, Hoe, KL, Kim, DU, Park, HO, Salas-Pino, S, Heichinger, C and Nurse, P (2013) A genome-wide resource of cell cycle and cell shape genes of fission yeast. Open Biol 3:130053
Abstract	To identify near complete sets of genes required for the cell cycle and cell shape, we have visually screened a genome-wide gene deletion library of 4843 fission yeast deletion mutants (95.7% of total protein encoding genes) for their effects on these processes. A total of 513 genes have been identified as being required for cell cycle progression, 276 of which have not been previously described as cell cycle genes. Deletions of a further 333 genes lead to specific alterations in cell shape and another 524 genes result in generally misshapen cells. Here, we provide the first eukaryotic resource of gene deletions, which describes a near genome-wide set of genes required for the cell cycle and cell shape.
Links	PubMed PMC3866870 Online version:10.1098/rsob.130053
Keywords	Cell Cycle/genetics; Computational Biology; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, cdc; Genome, Fungal; Humans; Mutagenesis; Phenotype; Schizosaccharomyces/cytology; Schizosaccharomyces/genetics; Schizosaccharomyces pombe Proteins/genetics
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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
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