id: ECO:0000077
name: methylation-specific polymerase chain reaction evidence
def: "A type of in vitro methylation assay evidence resulting from initial modification of DNA by sodium bisulfite, converting all unmethylated cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA." [PMC:38513, PMID:8790415]
synonym: "methylation-specific PCR evidence" EXACT []
synonym: "MS-PCR" EXACT []
synonym: "MSP" EXACT []
is_a: ECO:0001065 ! in vitro methylation assay evidence
relationship: IAO:0000136: GO:0006306 ! is about DNA methylation
relationship: OBI:0000312: OBI:0001684 ! is_specified_output_of methylation-specific polymerase chain reaction assay
comment: The product is the amplification of existing sequences - i.e. more DNA that can be further processed e.g. sequenced, DNA fingerprinting.
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