id: ECO:0001813
name: heteronuclear single quantum coherence spectroscopy evidence
def: "A type of nuclear magnetic resonance spectroscopy evidence based on two-dimensional NMR for elucidation of the chemical structure of an isolated or synthesized chemical compound where the characteristic transfer magnetization of a proton to a nitrogen or carbon isotope is monitored by NMR, generating a specific peak in the spectrum." [ECO:SW, PMID:19856946]
synonym: "HSQC" EXACT [PMID:19856946]
is_a: ECO:0001105 ! nuclear magnetic resonance spectroscopy evidence
comment: Chemical shifts in the spectrum indicating binding can be detected from analysis of a protein spectrum in the presence or absence of its cognate DNA binding site.
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