PMID:1101266

Citation	Watson, RJ, Parker, J, Fiil, NP, Flaks, JG and Friesen, JD (1975) New chromosomal location for structural genes of ribosomal proteins. Proc. Natl. Acad. Sci. U.S.A. 72:2765-9
Abstract	An Escherichia coli mutant, ts9, previously reported by Flaks et al. (Cold Spring Harbor Symp. Quant. Biol. 31, 623-631, 1966) to have an electrophoretically altered ribosomal protein, has been further characterized and the altered component has been identified as L7/L12. Although mutant ts9 is temperature sensitive for growth (rts-), the rts and L7/L12 mutations are genetically separable and are both located between argH and rif. The L7/L12 mutation (rpyL) maps very close to relC, mutants of which have a defect in the 50S ribosomal subunit. The gene order is argH-rts-(rpyL,relC)-rif. Protein synthesis directed by bacteriophage lambdacI857S7drifd18 in ultraviolet-irradiated cells indicates that L7/L12, As well as L1, L10, L11, and possibly L8 or L9 are coded by the phage DNA. Our results indicate that rpyL is the structural gene for L7/L12 and that this region of the E. coli chromosome contains a cluster of structural genes for ribosomal proteins.
Links	PubMed PMC432852
Keywords	Bacterial Proteins/biosynthesis; Chromosome Mapping; Chromosomes/metabolism; Electrophoresis, Polyacrylamide Gel; Escherichia coli/metabolism; Genes; Genotype; Mutation; Phenotype; Protein Biosynthesis; Ribosomal Proteins/biosynthesis; Temperature; Transcription, Genetic; Transduction, Genetic
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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
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