PMID:19144117
| Citation |
Rolain, JM, François, P, Hernandez, D, Bittar, F, Richet, H, Fournous, G, Mattenberger, Y, Bosdure, E, Stremler, N, Dubus, JC, Sarles, J, Reynaud-Gaubert, M, Boniface, S, Schrenzel, J and Raoult, D (2009) Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage.Biol. Direct 4:1 |
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| Abstract |
Staphylococcus aureus is a major human pathogen responsible for a variety of nosocomial and community-acquired infections. Recent reports show that the prevalence of Methicillin-Resistant S. aureus (MRSA) infections in cystic fibrosis (CF) patients is increasing. In 2006 in Marseille, France, we have detected an atypical MRSA strain with a specific antibiotic susceptibility profile and a unique growth phenotype. Because of the clinical importance of the spread of such strain among CF patients we decided to sequence the genome of one representative isolate (strain CF-Marseille) to compare this to the published genome sequences. We also conducted a retrospective epidemiological analysis on all S. aureus isolated from 2002 to 2007 in CF patients from our institution. |
| Links |
PubMed Online version:10.1186/1745-6150-4-1 |
| Keywords |
Anti-Bacterial Agents; Bacteriophages; Base Sequence; Cell Proliferation; Cell Wall; Cystic Fibrosis; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; France; Gene Expression Profiling; Genes, Bacterial; Genome, Bacterial; Humans; Methicillin Resistance; Minisatellite Repeats; Molecular Sequence Data; Phenotype; Phylogeny; Staphylococcus aureus; Transcription, Genetic |
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| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
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