PMID:340907
| Citation |
Pardo, D and Rosset, R (1977) Properties of ribosomes from erythromycin resistant mutants of Escherichia coli.Mol. Gen. Genet. 156:267-71 |
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| Abstract |
We have studied the in vitro properties of ribosomes from several mutants resistant to erythromycin. Mutations in three different genes may confer resistance to erythromycin. Two of them are structural genes for proteins L4 and L22 of the large subunit. The third mutation (in eryC gene) seems to affect mainly the small subunit. The mechanism of action of the antibiotic may involve both subunits. |
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| Keywords |
Drug Resistance, Microbial; Erythromycin; Escherichia coli; Genes; Ribosomal Proteins; Ribosomes |
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Main Points of the Paper
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Materials and Methods Used
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Phenotype Annotations
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| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|
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a mutation or genetic difference within a strain |
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OMP:0000276 |
increased resistance to antimicrobial compound |
Erythromycin resistance at the permissive temperatures above 32C |
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a mutation or genetic difference within a strain |
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OMP:0000276 |
increased resistance to antimicrobial compound |
Erythromycin resistance at the permissive temperatures above 32C |
| ||
| edit table |
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Notes
ECOID rplV: In vitro liquid broth.
OMP rplV: erythromycin term made. waiting for approval.
References
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