PMID:4571524

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Citation

Iwakura, Y, Ishihama, A and Yura, T (1973) RNA polymerase mutants of Escherichia coli. Streptolydigin resistance and its relation to rifampicin resistance.Mol. Gen. Genet. 121:181-96

Abstract

No abstract in PubMed

Links

PubMed

Keywords

Anti-Bacterial Agents; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Mutation; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Pyrans; Pyrroles; RNA; Rifampin

Main Points of the Paper

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Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

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Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: KY1343
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: rpoB
  • Genotype of Experimental Strain : rpoB
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

ECO:0000178

in vivo assay data

Resistance to Streptolydigin. in vivo.

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: KY1343
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: rpoB
  • Genotype of Experimental Strain : rpoB
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

ECO:0000182

in vitro culture assay data

Resistance to Streptolydigin. In vitro.


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Notes

ECO terms need to be more specific. Terms have been requested. In vivo solid PG medium. In vitro is a crude extracts. see table 2 comments for more detail.

OMP term: need to make term. Streptolydigin antbiotic resistance. Seems to block transcription but need to verify before submitting a new OMP term request.

References

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