PMID:4916925
| Citation |
Hazelbauer, GL, Mesibov, RE and Adler, J (1969) Escherichia coli mutants defective in chemotaxis toward specific chemicals. Proc. Natl. Acad. Sci. U.S.A. 64:1300-7 |
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| Abstract |
Mutants of Escherichia coli K12 have been found which fail to carry out chemotaxis toward certain chemicals only. One mutant exhibits greatly reduced chemotaxis toward L-serine but has no detectable defect either in uptake or in oxidative metabolism of that compound. Another mutant is not attracted to D-galactose and certain related sugars. There is a correlation between the galactose chemotaxis defect and a defect in galactose uptake, perhaps indicating a common component for chemotaxis and uptake systems. The results are discussed in terms of a model for chemotaxis in which attractants are detected by specific "chemoreceptors." |
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| Keywords |
Chemotaxis; Escherichia coli; Galactose/metabolism; Genetics, Microbial; Glucose/metabolism; Models, Biological; Mutation; Oxygen Consumption; Receptors, Drug; Ribose/metabolism; Serine/metabolism |
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Main Points of the Paper
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Materials and Methods Used
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Phenotype Annotations
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| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
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a mutation or genetic difference within a strain |
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OMP:0007041 |
decreased positive chemotaxis |
ECO:0000182 |
in vitro culture assay evidence |
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Notes
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