PMID:786287

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Citation

Manning, PA and Reeves, P (1976) Outer membrane of Escherichia coli K-12: TSX mutants (resistant to bacteriophage T6 and colicin K) lack an outer membrane protein. Biochem. Biophys. Res. Commun. 71:466-71

Abstract

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Links

PubMed

Keywords

Bacterial Proteins/deficiency; Bacterial Proteins/metabolism; Cell Membrane/metabolism; Colicins/pharmacology; Coliphages/metabolism; Drug Resistance, Microbial; Escherichia coli/drug effects; Escherichia coli/metabolism; Mutation; Species Specificity

Main Points of the Paper

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Materials and Methods Used

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Phenotype Annotations

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Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: P400
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: tsx+
  • Genotype of Experimental Strain : tsx mutation in P407
  • Reference Condition:

0000181

in vitro assay evidence

The tsx mutation was found to confer resistance toward the bacteriophage T6 by stopping the production of a membrane protein (the Tsx-protein) which is suspected of being involved in phage reception.

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: P400
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: con+ tsx+
  • Genotype of Experimental Strain : con and tsx double mutation in P1731
  • Reference Condition:

0000181

in vitro assay evidence

The con-tsx double mutation was found to confer resistance toward the bacteriophage T6 by stopping the production of a membrane protein (the Tsx-protien) which is suspected of being involved in phage reception.

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: P400
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: tsx+
  • Genotype of Experimental Strain : tsx mutation in P407
  • Reference Condition:

0000181

in vitro assay evidence

The tsx mutation was found to confer resistance toward Colicin K by stopping the production of a membrane protein (the Tsx-protein).

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: P400
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: con+ tsx+
  • Genotype of Experimental Strain : con and tsx double mutation in P1731
  • Reference Condition:

0000181

in vitro assay evidence

The con-tsx double mutation was found to confer resistance toward Colicin K by stopping the production of a membrane protein (the Tsx-protien).


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Notes

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