PMID:827549

Citation	Munch-Petersen, A and Mygind, B (1976) Nucleoside transport systems in Escherichia coli K12: specificity and regulation.J. Cell. Physiol. 89:551-9
Abstract	Two nucleoside transport systems have been verified and separated by mating and recombination experiments. The recipient strain was a mutant which is negative for transport of all nucleosides. The two systems differ in specificity and in regulation. One system transports pyrimidine and adenine nucleosides. It is regulated by the cytR gene. The other system transports all nucleosides and is regulated by the cytR as well as by the deoR genes. Enzyme assays performed on whole cells of strains, able or unable to transport nucleosides, indicate that the nucleoside catabolizing enzymes are located inside the permeability barrier of the cell.
Links	PubMed Online version:10.1002/jcp.1040890410
Keywords	Biological Transport, Active; Cytidine; Cytidine Deaminase; Escherichia coli; Genes, Regulator; Guanosine; Mutation; Nucleosides; Purine-Nucleoside Phosphorylase; Recombination, Genetic; Thymidine; Thymidine Phosphorylase; Uridine Phosphorylase
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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: NCBI Taxon ID: 83333	Genotype of Reference Strain: nupC nupG Genotype of Experimental Strain : nupC - nupG -	Reference Condition:	OMP:0000276	increased resistance to antimicrobial compound	ECO:0000094	biological assay data	Fluorouracil resistance
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: SO736 NCBI Taxon ID: 83333	Genotype of Reference Strain: gru Genotype of Experimental Strain : gru +	Reference Condition:	OMP:0000276	increased resistance to antimicrobial compound	ECO:0000094	biological assay data	resistant to showdomycin
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: NCBI Taxon ID: 83333	Genotype of Reference Strain: cru Genotype of Experimental Strain : cru +	Reference Condition:	OOMP:0000276	increased resistance to antimicrobial compound	ECO:0000094	biological assay data	Showdomycin sensitivty
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: NCBI Taxon ID: 83333	Genotype of Reference Strain: nupC nupG Genotype of Experimental Strain : nupC - nupG -	Reference Condition:	OMP:0000276	increased resistance to antimicrobial compound	ECO:0000094	biological assay data	Fluoruridine resistance
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: K-12 Substrain: NCBI Taxon ID: 83333	Genotype of Reference Strain: nupC nupG Genotype of Experimental Strain : nupC - nupG -	Reference Condition:	OMP:0000276	increased resistance to antimicrobial compound	ECO:0000094	biological assay data	Fluorodeoxycytidine resistance
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