Difference between revisions of "PMID:6344786"

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Revision as of 17:34, 26 June 2012

Citation

Jaffé, A, Chabbert, YA and Derlot, E (1983) Selection and characterization of beta-lactam-resistant Escherichia coli K-12 mutants.Antimicrob. Agents Chemother. 23:622-5

Abstract

beta-Lactam-resistant mutants of Escherichia coli K-12 were selected by using 12 different beta-lactam derivatives. The mutants fell into three categories showing (i) altered permeation through reduction or loss of outer membrane porin proteins (including ompF, ompR, and envZ alleles); (ii) increase in the rate of synthesis of chromosomally mediated beta-lactamase; or (iii) defective synthesis or action of cyclic adenosine 3',5'-phosphate (cya and crp alleles).

Links

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Keywords

Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Mutation; beta-Lactamases; beta-Lactams

Main Points of the Paper

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Materials and Methods Used

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Phenotype Annotations

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<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

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Notes

References

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