Difference between revisions of "PMID:3906038"

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{|  id="F4f8f4ac669954"  class=" tableEdit PMID_info_table" 
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!align=left  |Citation
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'''Hrebenda, J, Heleszko, H, Brzostek, K and Bielecki, J'''  (1985) Mutation affecting resistance of Escherichia coli K12 to nalidixic acid.''J. Gen. Microbiol.'' '''131''':2285-92
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!align=left  |Abstract
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A new mutation, nalD, determining resistance of Escherichia coli to nalidixic acid (NAL) is reported. The nalD mutant described is resistant to NAL at 37 degrees C but sensitive at 30 degrees C. It is defective in penetration of NAL and glycerol through the outer membrane at 37 degrees C. The nalD mutation is located half-way between 89 and 89.5 min on the E. coli genetic map.
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!align=left  |Links
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3906038 PubMed]
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!align=left  |Keywords
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Biological Transport; Cell Membrane Permeability; Chromosome Mapping; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Mutation; Nalidixic Acid
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==Main Points of the Paper ==
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{{LitSignificance}}
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== Materials and Methods Used ==
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{{LitMaterials}}
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==Phenotype Annotations==
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{|  id="S4f8f4ac66d9c6"  class=" tableEdit Phenotype_Table_2" 
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!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain: AB1157
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&p=mapview&p=has_linkout&p=blast_url&p=genome_blast&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''nalD<sup>+</sup>''
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*Genotype of Experimental Strain : ''nalD'' mutation in AB1157-81
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*Reference Condition: 30C
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*Experimental Condition: ''37C''
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OMP:0000276
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increased resistance to antibiotics
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ECO:0000182
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in vitro culture assay data
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Mutant is resistant to Nalidixic acid (NAL) at 37C and sensitive at 30C
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==Notes==
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==References==
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{{RefHelp}}
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<references/>
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[[Category:Publication]] [[Category:Papers referenced in the LaRossa chapter]]

Latest revision as of 13:41, 26 October 2012

Citation

Hrebenda, J, Heleszko, H, Brzostek, K and Bielecki, J (1985) Mutation affecting resistance of Escherichia coli K12 to nalidixic acid.J. Gen. Microbiol. 131:2285-92

Abstract

A new mutation, nalD, determining resistance of Escherichia coli to nalidixic acid (NAL) is reported. The nalD mutant described is resistant to NAL at 37 degrees C but sensitive at 30 degrees C. It is defective in penetration of NAL and glycerol through the outer membrane at 37 degrees C. The nalD mutation is located half-way between 89 and 89.5 min on the E. coli genetic map.

Links

PubMed

Keywords

Biological Transport; Cell Membrane Permeability; Chromosome Mapping; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Mutation; Nalidixic Acid

Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: AB1157
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: nalD+
  • Genotype of Experimental Strain : nalD mutation in AB1157-81
  • Reference Condition: 30C
  • Experimental Condition: 37C

OMP:0000276

increased resistance to antibiotics

ECO:0000182

in vitro culture assay data

Mutant is resistant to Nalidixic acid (NAL) at 37C and sensitive at 30C


</protect>

Notes

References

See Help:References for how to manage references in omp dev.