Difference between revisions of "PMID:6344786"

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{|  id="H4fea3906d6cdc"  class=" tableEdit PMID_info_table" 
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!align=left  |Citation
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'''Jaffé, A, Chabbert, YA and Derlot, E'''  (1983) Selection and characterization of beta-lactam-resistant Escherichia coli K-12 mutants.''Antimicrob. Agents Chemother.'' '''23''':622-5
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!align=left  |Abstract
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beta-Lactam-resistant mutants of Escherichia coli K-12 were selected by using 12 different beta-lactam derivatives. The mutants fell into three categories showing (i) altered permeation through reduction or loss of outer membrane porin proteins (including ompF, ompR, and envZ alleles); (ii) increase in the rate of synthesis of chromosomally mediated beta-lactamase; or (iii) defective synthesis or action of cyclic adenosine 3',5'-phosphate (cya and crp alleles).
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6344786 PubMed]
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!align=left  |Keywords
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Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Mutation; beta-Lactamases; beta-Lactams
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==Main Points of the Paper ==
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{{LitSignificance}}
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== Materials and Methods Used ==
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{{LitMaterials}}
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==Phenotype Annotations==
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="A4fea3906dc54c"  class=" tableEdit Phenotype_Table_2" 
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!|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status
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a mutation or genetic difference within a strain
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*Taxon: Escherichia coli
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*Strain: K-12
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*Substrain: B1389
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*NCBI Taxon ID: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=83333&lvl=3&lin=f&keep=1&srchmode=1&unlock 83333]
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*Genotype of Reference Strain: ''crp''
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*Genotype of Experimental Strain : ''crp'' in strain B1558
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*Reference Condition:
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OMP:0000276
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increased resistance to antimicrobial compound
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Resistance to Beta Lactams
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==Notes==
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==References==
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{{RefHelp}}
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<references/>
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[[Category:Publication]] [[Category:Papers referenced in the LaRossa chapter]] [[Category:LaRossa citations that need review]]

Latest revision as of 18:09, 23 January 2013

Citation

Jaffé, A, Chabbert, YA and Derlot, E (1983) Selection and characterization of beta-lactam-resistant Escherichia coli K-12 mutants.Antimicrob. Agents Chemother. 23:622-5

Abstract

beta-Lactam-resistant mutants of Escherichia coli K-12 were selected by using 12 different beta-lactam derivatives. The mutants fell into three categories showing (i) altered permeation through reduction or loss of outer membrane porin proteins (including ompF, ompR, and envZ alleles); (ii) increase in the rate of synthesis of chromosomally mediated beta-lactamase; or (iii) defective synthesis or action of cyclic adenosine 3',5'-phosphate (cya and crp alleles).

Links

PubMed

Keywords

Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Mutation; beta-Lactamases; beta-Lactams

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Main Points of the Paper

Please summarize the main points of the paper.

Materials and Methods Used

Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).

Phenotype Annotations

See Help:AnnotationTable for details on how to edit this table.
<protect>

Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

a mutation or genetic difference within a strain

  • Taxon: Escherichia coli
  • Strain: K-12
  • Substrain: B1389
  • NCBI Taxon ID: 83333
  • Genotype of Reference Strain: crp
  • Genotype of Experimental Strain : crp in strain B1558
  • Reference Condition:

OMP:0000276

increased resistance to antimicrobial compound

Resistance to Beta Lactams


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</protect>

Notes

References

See Help:References for how to manage references in omp dev.

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