PMID:4916925

Citation	Hazelbauer, GL, Mesibov, RE and Adler, J (1969) Escherichia coli mutants defective in chemotaxis toward specific chemicals. Proc. Natl. Acad. Sci. U.S.A. 64:1300-7
Abstract	Mutants of Escherichia coli K12 have been found which fail to carry out chemotaxis toward certain chemicals only. One mutant exhibits greatly reduced chemotaxis toward L-serine but has no detectable defect either in uptake or in oxidative metabolism of that compound. Another mutant is not attracted to D-galactose and certain related sugars. There is a correlation between the galactose chemotaxis defect and a defect in galactose uptake, perhaps indicating a common component for chemotaxis and uptake systems. The results are discussed in terms of a model for chemotaxis in which attractants are detected by specific "chemoreceptors."
Links	PubMed PMC223283
Keywords	Chemotaxis; Escherichia coli; Galactose/metabolism; Genetics, Microbial; Glucose/metabolism; Models, Biological; Mutation; Oxygen Consumption; Receptors, Drug; Ribose/metabolism; Serine/metabolism
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Phenotype Annotations

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Phenotype of	Taxon Information	Genotype Information (if known)	Condition Information	OMP ID	OMP Term Name	ECO ID	ECO Term Name	Notes	Status
a mutation or genetic difference within a strain	Taxon: Escherichia coli Strain: Escherichia coli K-12 Substrain: AW518 NCBI Taxon ID: 83333	Genotype of Reference Strain: tsr+ Genotype of Experimental Strain : tsr-1	Reference Condition: semisolid tryptone agar, 35C Experimental Condition: semisolid tryptone agar, 35C	OMP:0007041	decreased positive chemotaxis	ECO:0000182	in vitro culture assay evidence
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