Difference between revisions of "PMID:353502"
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| + | {| id="M4fe8f312bd960" class=" tableEdit PMID_info_table" | ||
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| + | !align=left |Citation | ||
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| + | '''Thorbjarnardóttir, SH, Magnúsdóttir, RA and Eggertsson, G''' (1978) Mutations determining generalized resistance to aminoglycoside antibiotics in Escherichia coli.''Mol. Gen. Genet.'' '''161''':89-98 | ||
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| + | !align=left |Abstract | ||
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| + | Mutations conferring resistance to low levels of kanamycin in Escherichia coli have been mapped at 3 locations: the unc locus (min. 83), a locus we have designated kanA (MIN. 72), close to strA (rpsL), and a locus at min. 86.5 previously discovered by Plate (1976) that we have designated ecfB. The unc and ecfB mutations are associated with defects in energy metabolism, while mutations at kanA may be in the gene coding for ribosomal protein S12 (rpsL). The three types of mutations cause cross resistance to a number of different aminoglycoside antibiotics and the effects of the mutations are cumulative in combination. | ||
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| + | !align=left |Links | ||
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| + | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=353502 PubMed] | ||
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| + | !align=left |Keywords | ||
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| + | Ampicillin; Chloramphenicol; Chromosome Mapping; Chromosomes, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Genes; Kanamycin; Penicillin Resistance; Tetracycline; Transduction, Genetic | ||
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| + | ==Main Points of the Paper == | ||
| + | {{LitSignificance}} | ||
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| + | == Materials and Methods Used == | ||
| + | {{LitMaterials}} | ||
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| + | ==Phenotype Annotations== | ||
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| + | {| id="G4fe8f312cf686" class=" tableEdit Phenotype_Table_2" | ||
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| + | !|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status | ||
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| + | ==Notes== | ||
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| + | ==References== | ||
| + | {{RefHelp}} | ||
| + | <references/> | ||
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| + | [[Category:Publication]] | ||
Revision as of 18:24, 25 June 2012
| Citation |
Thorbjarnardóttir, SH, Magnúsdóttir, RA and Eggertsson, G (1978) Mutations determining generalized resistance to aminoglycoside antibiotics in Escherichia coli.Mol. Gen. Genet. 161:89-98 |
|---|---|
| Abstract |
Mutations conferring resistance to low levels of kanamycin in Escherichia coli have been mapped at 3 locations: the unc locus (min. 83), a locus we have designated kanA (MIN. 72), close to strA (rpsL), and a locus at min. 86.5 previously discovered by Plate (1976) that we have designated ecfB. The unc and ecfB mutations are associated with defects in energy metabolism, while mutations at kanA may be in the gene coding for ribosomal protein S12 (rpsL). The three types of mutations cause cross resistance to a number of different aminoglycoside antibiotics and the effects of the mutations are cumulative in combination. |
| Links | |
| Keywords |
Ampicillin; Chloramphenicol; Chromosome Mapping; Chromosomes, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Genes; Kanamycin; Penicillin Resistance; Tetracycline; Transduction, Genetic |
| edit table |
Main Points of the Paper
Please summarize the main points of the paper.
Materials and Methods Used
Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).
Phenotype Annotations
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<protect>
| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|
| edit table |
</protect>
Notes
References
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