Difference between revisions of "PMID:6337120"
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| + | {| id="O504a772a871ef" class=" tableEdit PMID_info_table" | ||
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| + | !align=left |Citation | ||
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| + | '''Bogosian, G, Haydock, PV and Somerville, RL''' (1983) Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli.''J. Bacteriol.'' '''153''':1120-3 | ||
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| + | !align=left |Abstract | ||
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| + | Escherichia coli cells harboring a non-attenuated trp-lac operon fusion were used to evaluate the effects of indolmycin on the initiation of transcription at the trp promoter. Indolmycin caused repression in trpR+ strains and in trpR deletion mutants, although higher effector concentrations were required in the latter situation. Plasmid-mediated elevation in tryptophanyl-tRNA synthetase reversed the inhibitory effect of indolmycin. Indolmycin did not facilitate the binding of purified Trp repressor protein to trp operator DNA. | ||
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| + | !align=left |Links | ||
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| + | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6337120 PubMed] | ||
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| + | !align=left |Keywords | ||
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| + | Bacterial Proteins; DNA, Bacterial; Escherichia coli; Indoles; Mutation; Operon; Repressor Proteins; Transcription, Genetic; Tryptophan; Tryptophan-tRNA Ligase | ||
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| + | ==Main Points of the Paper == | ||
| + | {{LitSignificance}} | ||
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| + | == Materials and Methods Used == | ||
| + | {{LitMaterials}} | ||
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| + | ==Phenotype Annotations== | ||
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| + | {| id="H504a772a89ccf" class=" tableEdit Phenotype_Table_2" | ||
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| + | !|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status | ||
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| + | ==Notes== | ||
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| + | ==References== | ||
| + | {{RefHelp}} | ||
| + | <references/> | ||
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| + | [[Category:Publication]] | ||
Revision as of 17:37, 7 September 2012
| Citation |
Bogosian, G, Haydock, PV and Somerville, RL (1983) Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coli.J. Bacteriol. 153:1120-3 |
|---|---|
| Abstract |
Escherichia coli cells harboring a non-attenuated trp-lac operon fusion were used to evaluate the effects of indolmycin on the initiation of transcription at the trp promoter. Indolmycin caused repression in trpR+ strains and in trpR deletion mutants, although higher effector concentrations were required in the latter situation. Plasmid-mediated elevation in tryptophanyl-tRNA synthetase reversed the inhibitory effect of indolmycin. Indolmycin did not facilitate the binding of purified Trp repressor protein to trp operator DNA. |
| Links | |
| Keywords |
Bacterial Proteins; DNA, Bacterial; Escherichia coli; Indoles; Mutation; Operon; Repressor Proteins; Transcription, Genetic; Tryptophan; Tryptophan-tRNA Ligase |
| edit table |
Main Points of the Paper
Please summarize the main points of the paper.
Materials and Methods Used
Please list the materials and methods used in this paper (strains, plasmids, antibodies, etc).
Phenotype Annotations
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<protect>
| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|
| edit table |
</protect>
Notes
References
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