Difference between revisions of "PMID:781181"
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| + | {| id="R504cad580bd20" class=" tableEdit PMID_info_table" | ||
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| + | !align=left |Citation | ||
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| + | '''Săsărman, A, Desrochers, M, Sonea, S, Sanderson, KE and Surdeanu, M''' (1976) Porphobilinogen-accumulating mutants of Salmonella typhimurium LT2.''J. Gen. Microbiol.'' '''94''':359-66 | ||
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| + | !align=left |Abstract | ||
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| + | Four independent porphobilinogen-accumulating mutants of Salmonella typhimurium LT2 were isolated by selecting for dwarf colony formation on neomycin agar media. Cell-free extracts of the parent strain, but not of the mutants, were able to convert 5-aminolaevulinic acid or porphobilinogen to porphyrins. The results indicated that the mutants were deficient in uroporphyrinogen I synthase (EC. 4.3.I. 8) activity: these are the first mutants of this type reported in S. typhimurium LT2. Mapping of the hemC locus (for uroporphyrinogen I synthase) by F-mediated conjugation and by P22-mediated transduction showed the gene sequence ilvEDAC-hemC-cya-metE. | ||
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| + | !align=left |Links | ||
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| + | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=781181 PubMed] | ||
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| + | !align=left |Keywords | ||
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| + | Aminolevulinic Acid; Catalase; Cell-Free System; Chromosome Mapping; Conjugation, Genetic; Genes; Hydroxymethylbilane Synthase; Mutation; Porphobilinogen; Porphyrins; Salmonella typhimurium; Transduction, Genetic | ||
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| + | ==Main Points of the Paper == | ||
| + | {{LitSignificance}} | ||
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| + | == Materials and Methods Used == | ||
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| + | ==Phenotype Annotations== | ||
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| + | !|Phenotype of!!Taxon Information!!Genotype Information (if known)!!Condition Information!!OMP ID!!OMP Term Name!!ECO ID!!ECO Term Name!!Notes!!Status | ||
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| + | ==Notes== | ||
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| + | ==References== | ||
| + | {{RefHelp}} | ||
| + | <references/> | ||
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| + | [[Category:Publication]] | ||
Latest revision as of 09:53, 9 September 2012
| Citation |
Săsărman, A, Desrochers, M, Sonea, S, Sanderson, KE and Surdeanu, M (1976) Porphobilinogen-accumulating mutants of Salmonella typhimurium LT2.J. Gen. Microbiol. 94:359-66 |
|---|---|
| Abstract |
Four independent porphobilinogen-accumulating mutants of Salmonella typhimurium LT2 were isolated by selecting for dwarf colony formation on neomycin agar media. Cell-free extracts of the parent strain, but not of the mutants, were able to convert 5-aminolaevulinic acid or porphobilinogen to porphyrins. The results indicated that the mutants were deficient in uroporphyrinogen I synthase (EC. 4.3.I. 8) activity: these are the first mutants of this type reported in S. typhimurium LT2. Mapping of the hemC locus (for uroporphyrinogen I synthase) by F-mediated conjugation and by P22-mediated transduction showed the gene sequence ilvEDAC-hemC-cya-metE. |
| Links | |
| Keywords |
Aminolevulinic Acid; Catalase; Cell-Free System; Chromosome Mapping; Conjugation, Genetic; Genes; Hydroxymethylbilane Synthase; Mutation; Porphobilinogen; Porphyrins; Salmonella typhimurium; Transduction, Genetic |
| edit table |
Main Points of the Paper
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Materials and Methods Used
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Phenotype Annotations
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<protect>
| Phenotype of | Taxon Information | Genotype Information (if known) | Condition Information | OMP ID | OMP Term Name | ECO ID | ECO Term Name | Notes | Status |
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</protect>
Notes
References
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