PMID:3906038

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Citation

Hrebenda, J, Heleszko, H, Brzostek, K and Bielecki, J (1985) Mutation affecting resistance of Escherichia coli K12 to nalidixic acid.J. Gen. Microbiol. 131:2285-92

Abstract

A new mutation, nalD, determining resistance of Escherichia coli to nalidixic acid (NAL) is reported. The nalD mutant described is resistant to NAL at 37 degrees C but sensitive at 30 degrees C. It is defective in penetration of NAL and glycerol through the outer membrane at 37 degrees C. The nalD mutation is located half-way between 89 and 89.5 min on the E. coli genetic map.

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Keywords

Biological Transport; Cell Membrane Permeability; Chromosome Mapping; Conjugation, Genetic; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Mutation; Nalidixic Acid

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Phenotype of Taxon Information Genotype Information (if known) Condition Information OMP ID OMP Term Name ECO ID ECO Term Name Notes Status

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